Pubblicazioni

@article{Tagliabue2020,
title = {Biomechanical modelling of probe to tissue interaction during ultrasound scanning},
author = {Eleonora Tagliabue, Diego Dall’Alba, Enrico Magnabosco, Igor Peterlik, Paolo Fiorini},
editor = {Springer},
url = {https://link.springer.com/article/10.1007/s11548-020-02183-2?wt_mc=Internal.Event.1.SEM.ArticleAuthorOnlineFirst&utm_source=ArticleAuthorOnlineFirst&utm_medium=email&utm_content=AA_en_06082018&ArticleAuthorOnlineFirst_20200523#citeas},
doi = {https://doi.org/10.1007/s11548-020-02183-2},
year = {2020},
date = {2020-05-22},
journal = {International Journal of Computer Assisted Radiology and Surgery},
abstract = {Purpose

Biomechanical simulation of anatomical deformations caused by ultrasound probe pressure is of outstanding importance for several applications, from the testing of robotic acquisition systems to multi-modal image fusion and development of ultrasound training platforms. Different approaches can be exploited for modelling the probe–tissue interaction, each achieving different trade-offs among accuracy, computation time and stability.
Methods

We assess the performances of different strategies based on the finite element method for modelling the interaction between the rigid probe and soft tissues. Probe–tissue contact is modelled using (i) penalty forces, (ii) constraint forces, and (iii) by prescribing the displacement of the mesh surface nodes. These methods are tested in the challenging context of ultrasound scanning of the breast, an organ undergoing large nonlinear deformations during the procedure.
Results

The obtained results are evaluated against those of a non-physically based method. While all methods achieve similar accuracy, performance in terms of stability and speed shows high variability, especially for those methods modelling the contacts explicitly. Overall, prescribing surface displacements is the approach with best performances, but it requires prior knowledge of the contact area and probe trajectory.
Conclusions

In this work, we present different strategies for modelling probe–tissue interaction, each able to achieve different compromises among accuracy, speed and stability. The choice of the preferred approach highly depends on the requirements of the specific clinical application. Since the presented methodologies can be applied to describe general tool–tissue interactions, this work can be seen as a reference for researchers seeking the most appropriate strategy to model anatomical deformation induced by the interaction with medical tools.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{menegozzo2019automatic,
title = {Automatic process modeling with time delay neural network based on low-level data.},
author = {Giovanni Menegozzo and Diego Dall’Alba and Andrea Roberti and Paolo Fiorini},
url = {https://www.sciencedirect.com/science/article/pii/S2351978920300172/pdf?md5=92de1e9af7b7717c4a79e0a7ab8872f4&pid=1-s2.0-S2351978920300172-main.pdf},
year = {2019},
date = {2019-06-24},
journal = {Procedia Manufacturing},
volume = {38},
pages = {125--132},
publisher = {Elsevier},
abstract = {Automatic process modelling (APM) is an enabling technology for the development of intelligent manufacturingsystems (IMSs). The analysis of obtained models enables the prompt detection of error-prone steps and the design of proper mitigation strategies, in all aspects of the manufacturing process, from parameter optimization to development of customized personnel training. In this work we propose a Time Delay Neural Network (TDNN) applied to low level data for the automatic recognition of different process phases in industrial collaborative tasks.
We selected TDNN because they are suited for modelling time dependent processes over long sequences while maintaining computational efficiency. To experimentally evaluate the recognition performance and the generalization capability of the proposed method, we acquired two novel datasets reproducing a typical IMS setting. Datasets (including manually annotated ground-truth labels) are publicly available to enable other methods to be tested on them and they replicate typical Industry 4.0 setting. The first dataset replicates a collaborative robotic environment where a human operator interacts with a robotic manipulator in the execution of a pick and place task.
The second set represents a human tele-operated robotic assisted manipulation for assembly applications. The obtained results are superior to other methods available in literature and demonstrate an improved computational performance.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{tagliabue2019positionb,
title = {Position-based modeling of lesion displacement in Ultrasound-guided breast biopsy},
author = {Eleonora Tagliabue and Diego Dall’Alba and Enrico Magnabosco and Chiara Tenga and Igor Peterl{'i}k and Paolo Fiorini},
url = {https://link.springer.com/article/10.1007/s11548-019-01997-z},
doi = {https://doi.org/10.1007/s11548-019-01997-z},
year = {2019},
date = {2019-01-01},
journal = {International journal of computer assisted radiology and surgery},
volume = {14},
number = {8},
pages = {1329--1339},
publisher = {Springer},
abstract = {Purpose

Although ultrasound (US) images represent the most popular modality for guiding breast biopsy, malignant regions are often missed by sonography, thus preventing accurate lesion localization which is essential for a successful procedure. Biomechanical models can support the localization of suspicious areas identified on a preoperative image during US scanning since they are able to account for anatomical deformations resulting from US probe pressure. We propose a deformation model which relies on position-based dynamics (PBD) approach to predict the displacement of internal targets induced by probe interaction during US acquisition.


Methods

The PBD implementation available in NVIDIA FleX is exploited to create an anatomical model capable of deforming online. Simulation parameters are initialized on a calibration phantom under different levels of probe-induced deformations; then, they are fine-tuned by minimizing the localization error of a US–visible landmark of a realistic breast phantom. The updated model is used to estimate the displacement of other internal lesions due to probe-tissue interaction.


Results

The localization error obtained when applying the PBD model remains below 11 mm for all the tumors even for input displacements in the order of 30 mm. This proposed method obtains results aligned with FE models with faster computational performance, suitable for real-time applications. In addition, it outperforms rigid model used to track lesion position in US-guided breast biopsies, at least halving the localization error for all the displacement ranges considered.
Conclusion

Position-based dynamics approach has proved to be successful in modeling breast tissue deformations during US acquisition. Its stability, accuracy and real-time performance make such model suitable for tracking lesions displacement during US-guided breast biopsy.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{cheng2019design,
title = {Design and integration of electrical bio-impedance sensing in surgical robotic tools for tissue identification and display},
author = {Zhuoqi Cheng and Diego DallÁlba and Simone Foti and Andrea Mariani and Thibaud Jean Eudes Chupin and Darwin Gordon Caldwell and Giancarlo Ferrigno and Elena De Momi and Leonardo S Mattos and Paolo Fiorini},
url = {https://www.frontiersin.org/articles/10.3389/frobt.2019.00055/full},
doi = {https://doi.org/10.3389/frobt.2019.00055},
year = {2019},
date = {2019-01-01},
journal = {Frontiers in Robotics and AI},
volume = {6},
pages = {55},
publisher = {Frontiers},
abstract = {The integration of intra-operative sensors into surgical robots is a hot research topic since this can significantly facilitate complex surgical procedures by enhancing surgical awareness with real-time tissue information. However, currently available intra-operative sensing technologies are mainly based on image processing and force feedback, which normally require heavy computation or complicated hardware modifications of existing surgical tools. This paper presents the design and integration of electrical bio-impedance sensing into a commercial surgical robot tool, leading to the creation of a novel smart instrument that allows the identification of tissues by simply touching them. In addition, an advanced user interface is designed to provide guidance during the use of the system and to allow augmented-reality visualization of the tissue identification results. The proposed system imposes minor hardware modifications to an existing surgical tool, but adds the capability to provide a wealth of data about the tissue being manipulated. This has great potential to allow the surgeon (or an autonomous robotic system) to better understand the surgical environment. To evaluate the system, a series of ex-vivo experiments were conducted. The experimental results demonstrate that the proposed sensing system can successfully identify different tissue types with 100% classification accuracy. In addition, the user interface was shown to effectively and intuitively guide the user to measure the electrical impedance of the target tissue, presenting the identification results as augmented-reality markers for simple and immediate recognition.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{tagliabue2019positionb,
title = {Position-based modeling of lesion displacement in Ultrasound-guided breast biopsy},
author = {Eleonora Tagliabue and Diego Dall’Alba and Enrico Magnabosco and Chiara Tenga and Igor Peterl{'i}k and Paolo Fiorini},
url = {https://link.springer.com/article/10.1007/s11548-019-01997-z},
year = {2019},
date = {2019-01-01},
journal = {International journal of computer assisted radiology and surgery},
volume = {14},
number = {8},
pages = {1329--1339},
publisher = {Springer},
abstract = {Purpose

Although ultrasound (US) images represent the most popular modality for guiding breast biopsy, malignant regions are often missed by sonography, thus preventing accurate lesion localization which is essential for a successful procedure. Biomechanical models can support the localization of suspicious areas identified on a preoperative image during US scanning since they are able to account for anatomical deformations resulting from US probe pressure. We propose a deformation model which relies on position-based dynamics (PBD) approach to predict the displacement of internal targets induced by probe interaction during US acquisition.
Methods

The PBD implementation available in NVIDIA FleX is exploited to create an anatomical model capable of deforming online. Simulation parameters are initialized on a calibration phantom under different levels of probe-induced deformations; then, they are fine-tuned by minimizing the localization error of a US–visible landmark of a realistic breast phantom. The updated model is used to estimate the displacement of other internal lesions due to probe-tissue interaction.
Results

The localization error obtained when applying the PBD model remains below 11 mm for all the tumors even for input displacements in the order of 30 mm. This proposed method obtains results aligned with FE models with faster computational performance, suitable for real-time applications. In addition, it outperforms rigid model used to track lesion position in US-guided breast biopsies, at least halving the localization error for all the displacement ranges considered.
Conclusion

Position-based dynamics approach has proved to be successful in modeling breast tissue deformations during US acquisition. Its stability, accuracy and real-time performance make such model suitable for tracking lesions displacement during US-guided breast biopsy.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

@article{cheng2019designc,
title = {Design and integration of electrical bio-impedance sensing in surgical robotic tools for tissue identification and display},
author = {Zhuoqi Cheng and Diego DallÁlba and Simone Foti and Andrea Mariani and Thibaud Jean Eudes Chupin and Darwin Gordon Caldwell and Giancarlo Ferrigno and Elena De Momi and Leonardo S Mattos and Paolo Fiorini},
doi = {10.3389/frobt.2019.00055},
isbn = {22969144},
year = {2019},
date = {2019-01-01},
journal = {Frontiers in Robotics and AI},
volume = {6},
pages = {55},
publisher = {Frontiers},
abstract = {The integration of intra-operative sensors into surgical robots is a hot research topic since this can significantly facilitate complex surgical procedures by enhancing surgical awareness with real-time tissue information. However, currently available intra-operative sensing technologies are mainly based on image processing and force feedback, which normally require heavy computation or complicated hardware modifications of existing surgical tools. This paper presents the design and integration of electrical bio-impedance sensing into a commercial surgical robot tool, leading to the creation of a novel smart instrument that allows the identification of tissues by simply touching them. In addition, an advanced user interface is designed to provide guidance during the use of the system and to allow augmented-reality visualization of the tissue identification results. The proposed system imposes minor hardware modifications to an existing surgical tool, but adds the capability to provide a wealth of data about the tissue being manipulated. This has great potential to allow the surgeon (or an autonomous robotic system) to better understand the surgical environment. To evaluate the system, a series of ex-vivo experiments were conducted. The experimental results demonstrate that the proposed sensing system can successfully identify different tissue types with 100% classification accuracy. In addition, the user interface was shown to effectively and intuitively guide the user to measure the electrical impedance of the target tissue, presenting the identification results as augmented-reality markers for simple and immediate recognition.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}